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Malformations of cortical development (MCD) encompass a group of congenital disorders that disrupt normal brain cortical development due to genetic, infectious, vascular, or metabolic factors [1, 2–3]. Based on the disruption of key stages of cortical development, MCD are classified into three subtypes: abnormal cell proliferation and apoptosis, abnormal cell migration, and abnormal post-migrational...
Miao Pu et al.
BMC Medicine 2025; 23(1): 198
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Miao Pu et al.
BMC Medicine 2025; 23(1): 198
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Hearing loss is a significant public health concern. According to the World Health Organization (WHO), more than 1.5 billion individuals are affected by hearing loss, of whom approximately 430 million worldwide experience moderate or higher levels of hearing loss [1]. Hearing loss is not merely a sensory impairment that ranks as the fifth leading cause of disability worldwide and is linked...
Yu Yuxuan et al.
Journal of Health, Population and Nutrition 2025; 44(1): 110
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Yu Yuxuan et al.
Journal of Health, Population and Nutrition 2025; 44(1): 110
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Individuals with rare conditions, such as rare congenital malformations and/or intellectual disability, often face long diagnostic journeys and unmet healthcare needs [1]. Healthcare professionals may lack the knowledge to manage these rare and complex conditions effectively. European Reference Networks (ERNs) have been established as virtual networks of healthcare providers to facilitate collaboration...
Klein Haneveld Mirthe Jasmijn et al.
Orphanet Journal of Rare Diseases 2025; 20(1): 169
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Klein Haneveld Mirthe Jasmijn et al.
Orphanet Journal of Rare Diseases 2025; 20(1): 169
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Thyroid neoplasms are common malignancies of the endocrine system, with differentiated thyroid cancer (DTC) accounting for more than 95% of all tumor incidences [1, 2]. Distinct from other systemic neoplastic diseases, DTC usually have a relatively favorable prognosis and rarely develop distant metastases. At present, the pathological features of DTC with significant correlation with prognosis are...
Chen Xiao et al.
BMC Surgery 2025; 25(1): 150
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Chen Xiao et al.
BMC Surgery 2025; 25(1): 150
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