À LA UNE de l'actualité médicale

Determining the prognosis of patients with primary sclerosing cholangitis (PSC) is challenging. The natural history of patients with PSC is variable but frequently culminates in end-stage liver disease. The clinical course of PSC is complicated by an increased lifetime risk of up to 15% for cholangiocarcinoma (CCA) and, in case of concomitant inflammatory bowel disease (IBD), colorectal carcinoma (CRC)...

Keshoofi Pedram et al.
BMC Gastroenterology 2024; 24(1): 145
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The outcomes of lung transplant recipients infected with coronavirus disease 2019. (COVID-19) are poor [1]. To date, an appropriate treatment strategy for COVID-19 infection in lung transplant recipients has not been established [2]. Some small retrospective studies have provided suggestions for lung transplant patients, whereby stopping immunosuppressants such as mycophenolate or mTOR inhibitor and...

Lo Chien-Ming et al.
Journal of Cardiothoracic Surgery 2024; 19(1): 132
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In the recent decades, novel culture-independent techniques for microbial identification have demonstrated that the lungs harbor complex and dynamic communities of microbiota [1]. Lung microbiota communities differ significantly between healthy and diseased states [1]. Analogously, the lung microbiota of transplanted lungs is profoundly altered compared to that of healthy population [2–4]. Dysbiosis...

Lian Qiaoyan et al.
Respiratory Research 2024; 25(1): 125
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Infections are one of the most frequent complications of lung transplantation (LT) and the most common cause of death during the first year, with a mortality rate up to 37% [1, 2]. Overall prevalence of Gram-negative (GN) infections is annually increasing (4.33/1000 recipient-days) [3–6]. The prevalence of multidrug-resistant (MDR) GN bacteria is around 30% after LT, with an in-hospital mortality...

Congedi Sabrina et al.
BMC Infectious Diseases 2024; 24(1): 301
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