À LA UNE de la Rhumatologie
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Number of contiguous vertebral cross-links in the spine indicates bone formation: a cross-sectional study
In diffuse idiopathic skeletal hyperostosis (DISH), a continuous and measurable osteogenesis process involves development from incomplete and pointy bone bridges to more flowing and complete bridges [1]. The formation of bone cross-links is caused by ectopic ossification in which the anterolateral ligament component of the vertebral bodies becomes an osteophyte [2]. Diseases with high propensity for... Lire la suite
BMC Musculoskeletal Disorders 2023; 24(1):...
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An in vivo study to investigate an original intramedullary bone graft harvesting technology
Bone graft (BG) collected from the medullary canal of lower leg long bones is well-recognized for its bone regenerative capacity [1]. For historical and biological reasons, autologous BG is considered the gold standard among graft materials [2]. Indeed, autologous BG is the only graft material that fulfils all three components of the regeneration triad, namely, being of high osteogenic, osteoinductive,... Lire la suite
European journal of medical research 2023;...
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Exosomes derived from LPS-preconditioned bone marrow-derived MSC modulate macrophage plasticity to promote allograft survival via the NF-κB/NLRP3...
In the face of end-stage organ failure, organ transplantation has been recognized as one of the most effective treatments, but graft rejection raises a great challenge for long-term graft survival [1]. In transplantation biology, how to induce transplantation tolerance while avoiding long-term immunosuppression remains a key goal of research [2]. Recent articles have shown that macrophages are associated... Lire la suite
Journal of Nanobiotechnology 2023; 21(1):...
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Pantoprazole-Induced Bone Loss through Gastrin Secretion: A Stereological Study
Proton pump inhibitors (PPIs) are among the most widely prescribed drug classes worldwide [1]. They are potent gastric acid-suppressing drugs used to prevent or treat peptic ulcers, gastroesophageal reflux disease (GERD), and erosive esophagitis [2]. In spite of the evident clinical benefits of PPIs, recent epidemiological studies have raised concerns about their side effects after long-term use [3,... Lire la suite
BioMed Research International 2023 (2023),...
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