À LA UNE de la Rhumatologie
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The effect of the whole-process care model of the medical union on the improvement of kinesiophobia and bone mineral density in patients with osteoporosis...
Osteoporosis is a systemic bone disease, which leads to bone thinning, thus increasing the risk of fracture. A prospective cohort study in Australia [1] found that early treatment of osteoporosis can reduce the risk of fracture in patients. Therefore, there is a need to improve nursing. Osteoporosis mainly affects middle-aged and elderly people. Osteoporosis induced fractures have become an important... Lire la suite
Journal of Orthopaedic Surgery and Research...
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An innovative lab-scale production for a novel therapeutic DNA vaccine candidate against rheumatoid arthritis
In recent years, substantial progress has been made in the development of tolerating DNA vaccines as a novel strategy for the treatment of rheumatoid arthritis (RA) [1–4]. Among these major advances, our therapeutic pcDNA-CCOL2A1 vaccine is the most prominent because it is the first antigen-specific tolerising DNA vaccine encoding chicken type II collagen with a 4837 bp full-length cDNA... Lire la suite
Journal of Biological Engineering 2024; 18(1):...
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Temporal gene expression profiling during early-stage traumatic temporomandibular joint bony ankylosis in a sheep model
Temporomandibular joint (TMJ) ankylosis, characterised by a progressive limitation of mouth opening, is a pathological condition in which the mandible condyle is fused to the glenoid fossa by fibrous or bony tissues [1]. Traumatic TMJ ankylosis—the predominant form of the disease—is one of the most serious sequelae secondary to TMJ trauma, which not only affects the morphology of the oral... Lire la suite
BMC Oral Health 2024; 24(1): 284
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Inhibition of Oxidative Stress-Induced Ferroptosis Can Alleviate Rheumatoid Arthritis in Human
The clinical manifestations of rheumatoid arthritis (RA) are morning stiffness, symmetrical polyarticular swelling and pain, joint stiffness, and even deformation. The basic pathological changes of RA are pannus formation and synovial hyperplasia, resulting in the damage and erosion of subchondral bone and articular cartilage, with a high teratogenic rate, which greatly influences the well-being of... Lire la suite
Journal of Immunology Research 2024 (2024),...
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