À LA UNE de l'actualité médicale
01 - Identification of pleiotropy at the gene level between psychiatric disorders and related traits
Many mental disorders share features such as clinical symptoms, cognitive deficits or drug prescriptions. This overlap has led to arguments for treating mental disorders along symptom spectrums rather than as separate diagnostic categories. The genetic architectures of many mental illnesses, cognitive phenotypes and brain morphology traits also display many general similarities as they are highly heritable...
Polushina Tatiana et al.
Translational Psychiatry 2021; 11(1): 410
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Polushina Tatiana et al.
Translational Psychiatry 2021; 11(1): 410
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Bipolar disorder (BD) and major depressive disorder (MDD) are chronic, severe and recurrent mood disorders with substantial disease burden1. As these two psychiatric conditions both involve severe depressive symptoms, misdiagnosis of BD as unipolar depression is a serious clinical problem2. Previous studies suggested that C-reactive protein level3 and heart rate variability4 are candidate biomarkers...
Kim Sungkean et al.
Scientific reports 2020; 10(1): 12831
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Kim Sungkean et al.
Scientific reports 2020; 10(1): 12831
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In this review, the authors discuss the role of long-acting injectable antipsychotics (LAIs) for schizophrenia, focusing on the effectiveness and new perspectives introduced by such treatment strategy. Despite their promising pharmacokinetic features and their potential advantages in medication adherence, clinical outcomes, and medical costs, LAIs are not habitually presented as an option for patients,...
Renato de Filippis et al.
Expert Opinion on Drug Safety 2021; 20(7): 771-90
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Renato de Filippis et al.
Expert Opinion on Drug Safety 2021; 20(7): 771-90
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Electroconvulsive therapy (ECT) remains the most well-established treatment for patients with refractory depression. Although routinely used for severe unremitting forms of depression, it has substantial negative side-effects including cognitive side effects (i.e. impairment of attention and memory) [5] which can be distressing for patients and their families. Magnetic Seizure Therapy (MST) is similar...
Danielle Postorivo et al.
Current Treatment Options in Psychiatry 2021; 8(3): 141-57
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Danielle Postorivo et al.
Current Treatment Options in Psychiatry 2021; 8(3): 141-57
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Electroconvulsive therapy (ECT) is an effective treatment for numerous psychiatric conditions but commonly used in the management of severe and refractory depression.1 Numerous studies suggest that ECT is equally efficacious in treating both unipolar and bipolar depression.2-6 This modality is also shown to be effective in treating adults with bipolar mania 7-10 and mixed mood episodes.11-14
Overall...
Morcos, Nicholas MD et al.
Journal of ECT 2021; 37(3): 182-8
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Morcos, Nicholas MD et al.
Journal of ECT 2021; 37(3): 182-8
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