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Although antiretroviral treatment (ART) reduces HIV replication, HIV remains present and active in the central nervous system (CNS), where it can cause cognitive and mental health disorders, including HIV-associated neurocognitive disorders (HAND) [1]. HAND is a heterogeneous syndrome that has been linked to several biological mechanisms and clinical risk factors. These include neuroinflammation [2],...

Avdoshina, Valeria et al.
AIDS 2020; 34(7): 979-88
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Despite some conflicting reports, several studies have reported worse neurodevelopment in HIV-exposed uninfected (HEU) compared with HIV-unexposed uninfected infants and children.1-5 In utero atazanavir exposure has been reported in previous U.S. studies to be associated with language delay,6,7 and a South African study reported an association between cumulative maternal viremia and poor...

Jao, Jennifer Md, Mph et al.
Journal of AIDS 2020; 84(2): 213-9
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Although it has dramatically decreased in recent years, vertical transmission of HIV persists in the UK [1]; the National Study of HIV in Pregnancy and Childhood (NSHPC) data shows that from 2005 to 2009 there were 7560 pregnancies in women with diagnosed HIV infection, which had reduced to 4907 pregnancies in the period from 2015 to date. There were 31 cases of perinatal HIV transmission in 2006,...

A Hindocha et al.
HIV Medicine 2020; AOP: 10.1111/hiv.12862
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Because of the limitations of voluntary HIV testing (patient-initiated testing) and the insufficient coverage of HIV testing, the World Health Organization has recommended Provider-Initiated HIV Testing and Counseling (PITC) since 2007 [1]. PITC adoption in the majority of sub-Saharan countries has contributed significantly to the increase in HIV testing coverage [2,3,4]. Despite its systematic recommendation...

Maxime Inghels   et al.
AIDS and Behavior 2020; aop: 10.1007/s10461-020-02923-0
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